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DUSP2-mediated inhibition of tubular epithelial cell pyroptosis confers nephroprotection in acute kidney injury

Rationale: Acute kidney injury (AKI) is pathologically characterized by renal tubular epithelial cell (RTEC) death and interstitial inflammation, while their pathogenesis remains incompletely understood. Dual-specificity phosphatase 2 (DUSP2) recently emerges as a crucial regulator of cell death and...

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Detalles Bibliográficos
Autores principales: Xiong, Jiachuan, Ran, Li, Zhu, Yingguo, Wang, Yaqin, Wang, Shaobo, Wang, Yue, Lan, Qigang, Han, Wenhao, Liu, Yong, Huang, Yinghui, He, Ting, Li, Yan, Liu, Li, Zhao, Jinghong, Yang, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274747/
https://www.ncbi.nlm.nih.gov/pubmed/35836796
http://dx.doi.org/10.7150/thno.72291