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Histone acetyltransferases CBP/p300 in tumorigenesis and CBP/p300 inhibitors as promising novel anticancer agents

The histone acetyltransferases CBP and p300, often referred to as CBP/p300 due to their sequence homology and functional overlap and co-operation, are emerging as critical drivers of oncogenesis in the past several years. CBP/p300 induces histone H3 lysine 27 acetylation (H3K27ac) at target gene pro...

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Detalles Bibliográficos
Autores principales: Chen, Qingjuan, Yang, Binhui, Liu, Xiaochen, Zhang, Xu D., Zhang, Lirong, Liu, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274749/
https://www.ncbi.nlm.nih.gov/pubmed/35836809
http://dx.doi.org/10.7150/thno.73223