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Injectable electrospun fiber-hydrogel composite sequentially releasing clonidine and ropivacaine for prolonged and walking regional analgesia

Rationale: Peripheral nerve block is a traditional perioperative analgesic method for its precise pain control and low systemic toxicity. However, a single low dose of local anesthetic merely provides a few hours of analgesia, and high dose results in irreversible toxicity, whereas continuous infusi...

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Detalles Bibliográficos
Autores principales: Chen, Sufang, Yao, Weifeng, Wang, Haixia, Wang, Tienan, Xiao, Xue, Sun, Guoliang, Yang, Jing, Guan, Yu, Zhang, Zhen, Xia, Zhengyuan, Li, Mingqiang, Tao, Yu, Hei, Ziqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274753/
https://www.ncbi.nlm.nih.gov/pubmed/35836801
http://dx.doi.org/10.7150/thno.74845