Chondrocyte-specific genomic editing enabled by hybrid exosomes for osteoarthritis treatment

Rationale: A cell-specific delivery vehicle is required to achieve gene editing of the disease-associated cells, so the hereditable genome editing reactions are confined within these cells without affecting healthy cells. A hybrid exosome-based nano-sized delivery vehicle derived by fusion of engine...

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Detalles Bibliográficos
Autores principales: Liang, Yujie, Xu, Xiao, Xu, Limei, Iqbal, Zoya, Ouyang, Kan, Zhang, Huawei, Wen, Chunyi, Duan, Li, Xia, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274754/
https://www.ncbi.nlm.nih.gov/pubmed/35836795
http://dx.doi.org/10.7150/thno.69368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274754/
https://www.ncbi.nlm.nih.gov/pubmed/35836795
http://dx.doi.org/10.7150/thno.69368

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