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Chondrocyte-specific genomic editing enabled by hybrid exosomes for osteoarthritis treatment
Rationale: A cell-specific delivery vehicle is required to achieve gene editing of the disease-associated cells, so the hereditable genome editing reactions are confined within these cells without affecting healthy cells. A hybrid exosome-based nano-sized delivery vehicle derived by fusion of engine...
Autores principales: | Liang, Yujie, Xu, Xiao, Xu, Limei, Iqbal, Zoya, Ouyang, Kan, Zhang, Huawei, Wen, Chunyi, Duan, Li, Xia, Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274754/ https://www.ncbi.nlm.nih.gov/pubmed/35836795 http://dx.doi.org/10.7150/thno.69368 |
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