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Essential Role of Enzymatic Activity in the Leishmanicidal Mechanism of the Eosinophil Cationic Protein (RNase 3)

[Image: see text] The recruitment of eosinophils into Leishmania lesions is frequently associated with a favorable evolution. A feasible effector for this process is eosinophil cationic protein (ECP, RNase 3), one of the main human eosinophil granule proteins, endowed with a broad spectrum of antimi...

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Detalles Bibliográficos
Autores principales: Abengózar, María Ángeles, Fernández-Reyes, María, Salazar, Vivian A., Torrent, Marc, de la Torre, Beatriz G., Andreu, David, Boix, Ester, Rivas, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274760/
https://www.ncbi.nlm.nih.gov/pubmed/35731709
http://dx.doi.org/10.1021/acsinfecdis.1c00537