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Calcineurin Aα Contributes to IgE-Dependent Mast-Cell Mediator Secretion in Allergic Inflammation

Mast cells (MCs) are key mediators of allergic inflammation through the activation of cross-linked immunoglobulin E (IgE) bound to the high-affinity IgE receptor (FcϵRI) on the cell surface, leading to the release of biologically potent mediators, either from preformed granules or newly synthesized....

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Detalles Bibliográficos
Autores principales: Leong, Edwin, Pang, Zheng, Stadnyk, Andrew W., Lin, Tong-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274814/
https://www.ncbi.nlm.nih.gov/pubmed/34839285
http://dx.doi.org/10.1159/000520040