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Population Pharmacokinetics and Exposure‐Safety Relationships of Alisertib in Children and Adolescents With Advanced Malignancies
Population pharmacokinetic (PK) and exposure‐safety analyses of alisertib were performed in children enrolled in 2 clinical trials: NCT02444884 and NCT01154816. NCT02444884 was a dose‐finding study in children with relapsed/refractory solid malignancies (phase 1) or neuroblastomas (phase 2). Patient...
Hauptverfasser: | , , , , , , |
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Format: | Online Artikel Text |
Sprache: | English |
Veröffentlicht: |
John Wiley and Sons Inc.
2022
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Schlagworte: | |
Online Zugang: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274904/ https://www.ncbi.nlm.nih.gov/pubmed/34435684 http://dx.doi.org/10.1002/jcph.1958 |