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Increase in the Complement Activation Product C4d and the Terminal Complement Complex sC5b-9 Is Associated with Disease Severity and a Fatal Outcome in Necrotizing Soft-Tissue Infection

The hyperinflammatory burden is immense in necrotizing soft-tissue infection (NSTI). The complement system is a key during the innate immune response and may be a promising target to reduce the inflammatory response, potentially improving the clinical outcome. However, complement activation and its...

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Detalles Bibliográficos
Autores principales: Hedetoft, Morten, Madsen, Martin Bruun, Hansen, Cecilie Bo, Hyldegaard, Ole, Garred, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274942/
https://www.ncbi.nlm.nih.gov/pubmed/34903692
http://dx.doi.org/10.1159/000520496