SP1 Promotes HDAC4 Expression and Inhibits HMGB1 Expression to Reduce Intestinal Barrier Dysfunction, Oxidative Stress, and Inflammatory Response after Sepsis

As a serious and elusive syndrome caused by infection, sepsis causes a high rate of mortality around the world. Our investigation aims at exploring the role and possible mechanism of specificity protein-1 (SP1) in the development of sepsis. A mouse model of sepsis was established by cecal ligation p...

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Detalles Bibliográficos
Autores principales: Liu, Zhen-Mi, Wang, Xi, Li, Chen-Xi, Liu, Xue-Yan, Guo, Xiao-Jing, Li, Yang, Chen, You-Lian, Ye, Hong-Xing, Chen, Huai-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274949/
https://www.ncbi.nlm.nih.gov/pubmed/35780770
http://dx.doi.org/10.1159/000518277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274949/
https://www.ncbi.nlm.nih.gov/pubmed/35780770
http://dx.doi.org/10.1159/000518277

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