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Factors Limiting the Translatability of Rodent Model–Based Intranasal Vaccine Research to Humans

The intranasal route of vaccination presents an attractive alternative to parenteral routes and offers numerous advantages, such as the induction of both mucosal and systemic immunity, needle-free delivery, and increased patient compliance. Despite demonstrating promising results in preclinical stud...

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Detalles Bibliográficos
Autores principales: Cai, Lucy, Xu, Haiyue, Cui, Zhengrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274968/
https://www.ncbi.nlm.nih.gov/pubmed/35819736
http://dx.doi.org/10.1208/s12249-022-02330-9