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High AUF1 level in stromal fibroblasts promotes carcinogenesis and chemoresistance and predicts unfavorable prognosis among locally advanced breast cancer patients

BACKGROUND: Locally advanced breast cancer (LABC), the most aggressive form of the disease, is a serious threat for women's health worldwide. The AU-rich RNA-binding factor 1 (AUF1) promotes the formation of chemo-resistant breast cancer stem cells. Thereby, we investigated the power of AUF1 ex...

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Detalles Bibliográficos
Autores principales: Al-Tweigeri, Taher, AlRaouji, Noura N., Tulbah, Asma, Arafah, Maria, Aboussekhra, Mouad, Al-Mohanna, Falah, Gad, Ahmed Mostafa, Eldali, Abdelmonneim M., Elhassan, Tusneem A., Aboussekhra, Abdelilah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275022/
https://www.ncbi.nlm.nih.gov/pubmed/35821051
http://dx.doi.org/10.1186/s13058-022-01543-x