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Porphyromonas gingivalis Gingipains-Mediated Degradation of Plasminogen Activator Inhibitor-1 Leads to Delayed Wound Healing Responses in Human Endothelial Cells

Plasminogen activator inhibitor-1 (PAI-1), a serine protease inhibitor, is constitutively produced by endothelial cells and plays a vital role in maintaining vascular homeostasis. Chronic periodontitis is an inflammatory disease characterized by bleeding of periodontal tissues that support the tooth...

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Detalles Bibliográficos
Autores principales: Song, Li-Ting, Tada, Hiroyuki, Nishioka, Takashi, Nemoto, Eiji, Imamura, Takahisa, Potempa, Jan, Li, Chang-Yi, Matsushita, Kenji, Sugawara, Shunji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275039/
https://www.ncbi.nlm.nih.gov/pubmed/34823251
http://dx.doi.org/10.1159/000519737