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Porphyromonas gingivalis Gingipains-Mediated Degradation of Plasminogen Activator Inhibitor-1 Leads to Delayed Wound Healing Responses in Human Endothelial Cells
Plasminogen activator inhibitor-1 (PAI-1), a serine protease inhibitor, is constitutively produced by endothelial cells and plays a vital role in maintaining vascular homeostasis. Chronic periodontitis is an inflammatory disease characterized by bleeding of periodontal tissues that support the tooth...
Autores principales: | Song, Li-Ting, Tada, Hiroyuki, Nishioka, Takashi, Nemoto, Eiji, Imamura, Takahisa, Potempa, Jan, Li, Chang-Yi, Matsushita, Kenji, Sugawara, Shunji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275039/ https://www.ncbi.nlm.nih.gov/pubmed/34823251 http://dx.doi.org/10.1159/000519737 |
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