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Network analysis of synovial RNA sequencing identifies gene-gene interactions predictive of response in rheumatoid arthritis

BACKGROUND: To determine whether gene-gene interaction network analysis of RNA sequencing (RNA-Seq) of synovial biopsies in early rheumatoid arthritis (RA) can inform our understanding of RA pathogenesis and yield improved treatment response prediction models. METHODS: We utilized four well curated...

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Detalles Bibliográficos
Autores principales: Sciacca, Elisabetta, Surace, Anna E. A., Alaimo, Salvatore, Pulvirenti, Alfredo, Rivellese, Felice, Goldmann, Katriona, Ferro, Alfredo, Latora, Vito, Pitzalis, Costantino, Lewis, Myles J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275048/
https://www.ncbi.nlm.nih.gov/pubmed/35820911
http://dx.doi.org/10.1186/s13075-022-02803-z