Cargando…

DUB1 suppresses Hippo signaling by modulating TAZ protein expression in gastric cancer

BACKGROUND: The Hippo pathway functions as a tumor suppressor pathway in human cancers, while dysfunction of the Hippo pathway is frequently observed in malignancies. Although YAP/TAZ activity is tightly controlled by the phosphorylation cascade of the MST-LATS-YAP/TAZ axis, it is still unclear why...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Dehai, Li, Zhongbo, Li, Xin, Yan, Cheng, Yang, Huijie, Zhuang, Ting, Wang, Xiao, Zang, Yifeng, Liu, Ziping, Wang, Tianshi, Jiang, Rixia, Su, Peng, Zhu, Jian, Ding, Yinlu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275142/
https://www.ncbi.nlm.nih.gov/pubmed/35820928
http://dx.doi.org/10.1186/s13046-022-02410-5