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Inhibitory effects of anthracyclines on partially purified 5′–3′ DNA helicase of Plasmodium falciparum

BACKGROUND: Plasmodium falciparum has been becoming resistant to the currently used anti-malarial drugs. Searching for new drug targets is urgently needed for anti-malarial development. DNA helicases separating double-stranded DNA into single-stranded DNA intermediates are essential in nearly all DN...

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Detalles Bibliográficos
Autores principales: Rattaprasert, Pongruj, Suntornthiticharoen, Pattra, Limudomporn, Paviga, Thima, Kanthinich, Chavalitshewinkoon-Petmitr, Porntip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275250/
https://www.ncbi.nlm.nih.gov/pubmed/35821133
http://dx.doi.org/10.1186/s12936-022-04238-y