Shikonin derivatives cause apoptosis and cell cycle arrest in human chondrosarcoma cells via death receptors and MAPK regulation

BACKGROUND: Although chondrosarcoma is the second most common primary malignant bone tumor, treatment options are limited due to its extensive resistance to a chemo- and radiation therapy. Since shikonin has shown potent anticancer activity in various types of cancer cells, it represents a promising...

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Detalles Bibliográficos
Autores principales: Lohberger, Birgit, Glänzer, Dietmar, Kaltenegger, Heike, Eck, Nicole, Leithner, Andreas, Bauer, Rudolf, Kretschmer, Nadine, Steinecker-Frohnwieser, Bibiane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275282/
https://www.ncbi.nlm.nih.gov/pubmed/35820864
http://dx.doi.org/10.1186/s12885-022-09857-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275282/
https://www.ncbi.nlm.nih.gov/pubmed/35820864
http://dx.doi.org/10.1186/s12885-022-09857-x

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