Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements

Chronic Lymphocytic Leukemia (CLL) is characterized by the accumulation of monoclonal CD5(+) B cells with low surface immunoglobulins (IG). About 40% of CLL clones utilize quasi-identical B cell receptors, defined as stereotyped BCR. CLL-like stereotyped-IG rearrangements are present in normal B cel...

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Detalles Bibliográficos
Autores principales: Bagnara, Davide, Colombo, Monica, Reverberi, Daniele, Matis, Serena, Massara, Rosanna, Cardente, Niccolò, Ubezio, Gianluca, Agostini, Vanessa, Agnelli, Luca, Neri, Antonino, Cardillo, Martina, Vergani, Stefano, Ghiotto, Fabio, Mazzarello, Andrea Nicola, Morabito, Fortunato, Cutrona, Giovanna, Ferrarini, Manlio, Fais, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275393/
https://www.ncbi.nlm.nih.gov/pubmed/35837088
http://dx.doi.org/10.3389/fonc.2022.894419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275393/
https://www.ncbi.nlm.nih.gov/pubmed/35837088
http://dx.doi.org/10.3389/fonc.2022.894419

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