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Characterizing Features of Human Circulating B Cells Carrying CLL-Like Stereotyped Immunoglobulin Rearrangements
Chronic Lymphocytic Leukemia (CLL) is characterized by the accumulation of monoclonal CD5(+) B cells with low surface immunoglobulins (IG). About 40% of CLL clones utilize quasi-identical B cell receptors, defined as stereotyped BCR. CLL-like stereotyped-IG rearrangements are present in normal B cel...
Autores principales: | Bagnara, Davide, Colombo, Monica, Reverberi, Daniele, Matis, Serena, Massara, Rosanna, Cardente, Niccolò, Ubezio, Gianluca, Agostini, Vanessa, Agnelli, Luca, Neri, Antonino, Cardillo, Martina, Vergani, Stefano, Ghiotto, Fabio, Mazzarello, Andrea Nicola, Morabito, Fortunato, Cutrona, Giovanna, Ferrarini, Manlio, Fais, Franco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275393/ https://www.ncbi.nlm.nih.gov/pubmed/35837088 http://dx.doi.org/10.3389/fonc.2022.894419 |
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