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Targeted proteoform mapping uncovers specific Neurexin-3 variants required for dendritic inhibition

The diversification of cell adhesion molecules by alternative splicing is proposed to underlie molecular codes for neuronal wiring. Transcriptomic approaches mapped detailed cell-type-specific mRNA splicing programs. However, it has been hard to probe the synapse-specific localization and function o...

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Detalles Bibliográficos
Autores principales: Hauser, David, Behr, Katharina, Konno, Kohtarou, Schreiner, Dietmar, Schmidt, Alexander, Watanabe, Masahiko, Bischofberger, Josef, Scheiffele, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275415/
https://www.ncbi.nlm.nih.gov/pubmed/35550065
http://dx.doi.org/10.1016/j.neuron.2022.04.017