Obesity enriches for tumor protective microbial metabolites and treatment refractory cells to confer therapy resistance in PDAC

Obesity causes chronic inflammation and changes in gut microbiome. However, how this contributes to poor survival and therapy resistance in patients with pancreatic cancer remain undetermined. Our current study shows that high fat diet-fed obese pancreatic tumor bearing mice do not respond to standa...

Descripción completa

Detalles Bibliográficos
Autores principales: Kesh, Kousik, Mendez, Roberto, Mateo-Victoriano, Beatriz, Garrido, Vanessa T, Durden, Brittany, Gupta, Vineet K, Oliveras Reyes, Alfredo, Merchant, Nipun, Datta, Jashodeep, Banerjee, Santanu, Banerjee, Sulagna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275504/
https://www.ncbi.nlm.nih.gov/pubmed/35816618
http://dx.doi.org/10.1080/19490976.2022.2096328

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275504/
https://www.ncbi.nlm.nih.gov/pubmed/35816618
http://dx.doi.org/10.1080/19490976.2022.2096328

Ejemplares similares