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Obesity enriches for tumor protective microbial metabolites and treatment refractory cells to confer therapy resistance in PDAC
Obesity causes chronic inflammation and changes in gut microbiome. However, how this contributes to poor survival and therapy resistance in patients with pancreatic cancer remain undetermined. Our current study shows that high fat diet-fed obese pancreatic tumor bearing mice do not respond to standa...
Autores principales: | Kesh, Kousik, Mendez, Roberto, Mateo-Victoriano, Beatriz, Garrido, Vanessa T, Durden, Brittany, Gupta, Vineet K, Oliveras Reyes, Alfredo, Merchant, Nipun, Datta, Jashodeep, Banerjee, Santanu, Banerjee, Sulagna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275504/ https://www.ncbi.nlm.nih.gov/pubmed/35816618 http://dx.doi.org/10.1080/19490976.2022.2096328 |
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