Simulation and Machine Learning Methods for Ion-Channel Structure Determination, Mechanistic Studies and Drug Design

Ion channels are expressed in almost all living cells, controlling the in-and-out communications, making them ideal drug targets, especially for central nervous system diseases. However, owing to their dynamic nature and the presence of a membrane environment, ion channels remain difficult targets f...

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Detalles Bibliográficos
Autores principales: Zhu, Zhengdan, Deng, Zhenfeng, Wang, Qinrui, Wang, Yuhang, Zhang, Duo, Xu, Ruihan, Guo, Lvjun, Wen, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275593/
https://www.ncbi.nlm.nih.gov/pubmed/35837274
http://dx.doi.org/10.3389/fphar.2022.939555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275593/
https://www.ncbi.nlm.nih.gov/pubmed/35837274
http://dx.doi.org/10.3389/fphar.2022.939555

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