Exploring the Conformational Impact of Glycine Receptor TM1-2 Mutations Through Coarse-Grained Analysis and Atomistic Simulations

Pentameric ligand-gated ion channels (PLGICs) are a family of proteins that convert chemical signals into ion fluxes through cellular membranes. Their structures are highly conserved across all kingdoms from bacteria to eukaryotes. Beyond their classical roles in neurotransmission and neurological d...

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Detalles Bibliográficos
Autores principales: Mhashal, Anil Ranu, Yoluk, Ozge, Orellana, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275627/
https://www.ncbi.nlm.nih.gov/pubmed/35836931
http://dx.doi.org/10.3389/fmolb.2022.890851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275627/
https://www.ncbi.nlm.nih.gov/pubmed/35836931
http://dx.doi.org/10.3389/fmolb.2022.890851

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