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SARS-CoV-2 diverges from other betacoronaviruses in only partially activating the IRE1α/XBP1 ER stress pathway in human lung-derived cells

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has killed over 6 million individuals worldwide and continues to spread in countries where vaccines are not yet widely available, or its citizens are hesitant to become vaccinated. Therefore, it is critical to unravel the molecular mechani...

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Detalles Bibliográficos
Autores principales: Nguyen, Long C., Renner, David M., Silva, Diane, Yang, Dongbo, Parenti, Nicholas, Medina, Kaeri M., Nicolaescu, Vlad, Gula, Haley, Drayman, Nir, Valdespino, Andrea, Mohamed, Adil, Dann, Christopher, Wannemo, Kristin, Robinson-Mailman, Lydia, Gonzalez, Alan, Stock, Letícia, Cao, Mengrui, Qiao, Zeyu, Moellering, Raymond E., Tay, Savas, Randall, Glenn, Beers, Michael F., Rosner, Marsha Rich, Oakes, Scott A., Weiss, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275661/
https://www.ncbi.nlm.nih.gov/pubmed/35821981
http://dx.doi.org/10.1101/2021.12.30.474519