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A surface pocket in the cytoplasmic domain of the herpes simplex virus fusogen gB controls membrane fusion

Membrane fusion during the entry of herpesviruses is carried out by the viral fusogen gB that is activated by its partner protein gH in some manner. The fusogenic activity of gB is controlled by its cytoplasmic (or intraviral) domain (gB(CTD)) and, according to the current model, the gB(CTD) is a tr...

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Detalles Bibliográficos
Autores principales: Pataki, Zemplen, Sanders, Erin K., Heldwein, Ekaterina E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275723/
https://www.ncbi.nlm.nih.gov/pubmed/35767585
http://dx.doi.org/10.1371/journal.ppat.1010435