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PKC Inhibits Sec61 Translocon-Mediated Sarcoplasmic Reticulum Ca(2+) Leak in Smooth Muscle Cells

PKC inhibitors stimulate Ca(2+) release from internal stores in diverse cell types. Our data indicate that this action cannot be explained by an increased agonist-induced IP(3) production or an overloaded SR Ca(2+) pool in smooth muscle cells from guinea pig urinary bladder. The incubation of these...

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Detalles Bibliográficos
Autores principales: Dagnino-Acosta, Adan, Guerrero-Hernandez, Agustín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275787/
https://www.ncbi.nlm.nih.gov/pubmed/35837019
http://dx.doi.org/10.3389/fphys.2022.925023