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An Orthotopic Patient-Derived Xenograft (PDX) Model Allows the Analysis of Metastasis-Associated Features in Colorectal Cancer

Metastasis is the primary cause of death in patients with colorectal cancer (CRC), urging the need for preclinical models that recapitulate the metastatic process at the individual patient level. We used an orthotopic patient-derived xenograft (PDX) obtained through the direct implantation of freshl...

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Detalles Bibliográficos
Autores principales: De Angelis, Maria Laura, Francescangeli, Federica, Nicolazzo, Chiara, Xhelili, Eljona, La Torre, Filippo, Colace, Lidia, Bruselles, Alessandro, Macchia, Daniele, Vitale, Sara, Gazzaniga, Paola, Baiocchi, Marta, Zeuner, Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275818/
https://www.ncbi.nlm.nih.gov/pubmed/35837106
http://dx.doi.org/10.3389/fonc.2022.869485