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Triptolide inhibits oxidative stress and inflammation via the microRNA-155-5p/brain-derived neurotrophic factor to reduce podocyte injury in mice with diabetic nephropathy

Diabetic nephropathy (DN) is a complication of diabetes. This study sought to explore the mechanism of triptolide (TP) in podocyte injury in DN. DN mice were induced by high-fat diet&streptozocin and treated with TP. Fasting blood glucose, 24 h urine microalbumin (UMA), the pathological changes...

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Detalles Bibliográficos
Autores principales: Gao, Jian, Liang, Zheng, Zhao, Fei, Liu, Xiaojing, Ma, Ning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275869/
https://www.ncbi.nlm.nih.gov/pubmed/35603354
http://dx.doi.org/10.1080/21655979.2022.2067293