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Toll-like receptor 9 (TLR9) gene deletion-mediated fracture healing in type II diabetic osteoporosis associates with inhibition of the nuclear factor-kappa B (NF-κB) signaling pathway

Diabetes is characterized by increased fracture risk. Evidence from in vivo studies is lacking for anti-fracture strategies in diabetes. Our microarray analyses predicted association of Toll-like receptor 9 (TLR9) with both diabetes and osteoporosis, which was the focus of this work in a murine mode...

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Detalles Bibliográficos
Autores principales: Han, Jiakai, Zheng, Qian, Cheng, Yongxia, Liu, Yong, Bai, Yuxin, Yan, Bin, Guo, Sufen, Yu, Jianbo, Li, Xinxin, Wang, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275877/
https://www.ncbi.nlm.nih.gov/pubmed/35707851
http://dx.doi.org/10.1080/21655979.2022.2063663