Puerarin suppresses hypoxia-induced vascular endothelial growth factor upregulation in human retinal pigmented epithelial cells by blocking JAK2/STAT3 pathway

The purpose of this study was to explore the mechanism by which puerarin regulated the expression of hypoxia-inducible factor 1α (HIF-1α) and vascular endothelial growth factor (VEGF) in humans’ retinal pigment epithelial (RPE) cells under hypoxia. RPE cells (ARPE-19 and D407 cells) and a rat model...

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Detalles Bibliográficos
Autores principales: Tang, Huixin, Kong, Lingchun, Yang, Yuqin, Li, Jingjing, Zou, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275891/
https://www.ncbi.nlm.nih.gov/pubmed/35510332
http://dx.doi.org/10.1080/21655979.2022.2070586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275891/
https://www.ncbi.nlm.nih.gov/pubmed/35510332
http://dx.doi.org/10.1080/21655979.2022.2070586

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