BAY-885, a mitogen-activated protein kinase kinase 5 inhibitor, induces apoptosis by regulating the endoplasmic reticulum stress/Mcl-1/Bim pathway in breast cancer cells

The mitogen-activated protein kinase kinase 5 (MEK5)/extracellular signal-regulated kinase 5 (ERK5) axis has been reported to promote tumorigenesis in breast cancer (BC). Therefore, targeting the MEK5/ERK5 axis is a potential strategy against BC. BAY-885 is a novel inhibitor of ERK5; however, to dat...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Ji, Xiaochun, Mao, Chenxiao, Yu, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275924/
https://www.ncbi.nlm.nih.gov/pubmed/35609325
http://dx.doi.org/10.1080/21655979.2022.2078557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275924/
https://www.ncbi.nlm.nih.gov/pubmed/35609325
http://dx.doi.org/10.1080/21655979.2022.2078557

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