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Mitochondrial transcription factor B2 overexpression increases M2 macrophage infiltration via cytosolic mitochondrial DNA-stimulated Interleukin-6 secretion in ovarian cancer

Mitochondrial transcription factor B2 (TFB2M) is a protein modulating both mitochondrial DNA (mtDNA) transcription and compacting. In this study, we explored the expression profile of TFB2M in ovarian cancer, its association with infiltration of tumor-associated macrophages (TAMs), and its influence...

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Detalles Bibliográficos
Autores principales: Wu, Weilu, Zhou, Shijie, Liu, Tianmin, Liang, Dongni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275939/
https://www.ncbi.nlm.nih.gov/pubmed/35577351
http://dx.doi.org/10.1080/21655979.2022.2074615