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Shikonin inhibited glycolysis and sensitized cisplatin treatment in non-small cell lung cancer cells via the exosomal pyruvate kinase M2 pathway

The active ingredient of the traditional Chinese medicine comfrey is shikonin, a naphthoquinone compound. The focus of this study was to investigate the effect of shikonin on the proliferation, invasion, migration, and chemoresistance of non-small cell lung cancer (NSCLC) cells, and to explore its u...

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Detalles Bibliográficos
Autores principales: Dai, Yitian, Liu, Yuping, Li, Jingyi, Jin, Mingming, Yang, Hao, Huang, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275963/
https://www.ncbi.nlm.nih.gov/pubmed/35706397
http://dx.doi.org/10.1080/21655979.2022.2086378