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Identification of novel natural inhibitors targeting AKT Serine/Threonine Kinase 1 (AKT1) by computational study

Despite great progress, the current cancer treatments often have obvious toxicity and side effects. and a poor prognosis (some patients). One of the reasons for the poor prognosis is that certain enzymes prevent anticancer drugs from killing tumor cells. AKT1 is involved in regulating PI3K/AKT/mTOR,...

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Detalles Bibliográficos
Autores principales: Zhong, Sheng, Hou, Yuanyuan, Zhang, Zhiyun, Guo, Zhen, Yang, Wenzhuo, Dou, Gaojing, Lv, Xiaye, Wang, Xinhui, Ge, Junliang, Wu, Bo, Pan, Xuefeng, Wang, Hongyu, Yang, Qunying, Mou, Yonggao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275969/
https://www.ncbi.nlm.nih.gov/pubmed/35603567
http://dx.doi.org/10.1080/21655979.2021.2011631