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Metformin suppresses lung adenocarcinoma by downregulating long non-coding RNA (lncRNA) AFAP1-AS1 and secreted phosphoprotein 1 (SPP1) while upregulating miR-3163

AFAP1-AS1 plays a pro-tumor role in lung cancer. However, no investigation has focused on whether it is involved in the anticancer activity of metformin (Met) in the treatment of lung adenocarcinoma (LUAD). Reverse transcription quantitative polymerase chain reaction (RT-qPCR) was performed to detec...

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Detalles Bibliográficos
Autores principales: Qiu, Caiyu, Li, Chuanxiang, Zheng, Quan, Fang, Si, Xu, Jianqun, Wang, Hongjuan, Guo, Hongrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9275981/
https://www.ncbi.nlm.nih.gov/pubmed/35603556
http://dx.doi.org/10.1080/21655979.2021.2005981