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Salvianolic acid A (Sal A) suppresses malignant progression of glioma and enhances temozolomide (TMZ) sensitivity via repressing transgelin-2 (TAGLN2) mediated phosphatidylinositol-3-kinase (PI3K) / protein kinase B (Akt) pathway

Glioma originated from excessively proliferative and highly invaded glial cells is a common intracranial malignant tumor with poor prognosis. Resistance to temozolomide (TMZ) is a clinical challenge in glioma treatment due to the fact that chemoresistance remains a main obstacle in the improvement o...

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Detalles Bibliográficos
Autores principales: Ye, Tingting, Chen, Rongrong, Zhou, Yu, Zhang, Juan, Zhang, Zhongqin, Wei, Hui, Xu, Yan, Wang, Yulan, Zhang, Yinlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276020/
https://www.ncbi.nlm.nih.gov/pubmed/35505656
http://dx.doi.org/10.1080/21655979.2022.2070963