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D-4F, an apolipoprotein A-I mimetic, promotes the clearance of myelin debris and the reduction of foamy macrophages after spinal cord injury

After spinal cord injury (SCI), a large number of blood-derived macrophages infiltrate the lesion site and phagocytose myelin debris to become foamy macrophages, which leads to chronic inflammation. The drug D-4F, an apolipoprotein A-I peptidomimetic made of D-amino acids, has been reported to promo...

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Detalles Bibliográficos
Autores principales: Li, Jinxin, Zhu, Zhenyu, Li, Yiteng, Chen, Yihao, Hu, Xuyang, Liu, Yanchang, Shi, Yi, Hu, Yao, Bi, Yihui, Xu, Xinzhong, Zheng, Meige, Cheng, Li, Jing, Juehua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276047/
https://www.ncbi.nlm.nih.gov/pubmed/35546071
http://dx.doi.org/10.1080/21655979.2022.2073063