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Effective treatment in lung adenocarcinoma patient with brain metastases harboring novel CLHC1/RNT4 intergenic region- ALK fusion: A case report

RATIONALE: Anaplastic lymphoma kinase (ALK) fusion, an important oncogenic mutation, occurs in 3% to 7% of non-small cell lung cancer (NSCLC) cases, and EML4 is the most common partner gene. With the widespread application of next-generation sequencing (NGS), more gene breakpoint fusions have been d...

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Detalles Bibliográficos
Autores principales: Xia, Huanling, Liang, Binbin, Liu, Guoxiang, Qi, Yingxue, Luo, Ningning, Li, Mengmeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276468/
https://www.ncbi.nlm.nih.gov/pubmed/35446297
http://dx.doi.org/10.1097/MD.0000000000029134