The conserved helicase ZNFX-1 memorializes silenced RNAs in perinuclear condensates

RNA-mediated interference (RNAi) is a conserved mechanism that uses small RNAs (sRNAs) to silence gene expression. In the Caenorhabditis elegans germline, transcripts targeted by sRNAs are used as templates for sRNA amplification to propagate silencing into the next generation. Here we show that RNA...

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Detalles Bibliográficos
Autores principales: Ouyang, John Paul Tsu, Zhang, Wenyan Lucy, Seydoux, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276528/
https://www.ncbi.nlm.nih.gov/pubmed/35739318
http://dx.doi.org/10.1038/s41556-022-00940-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276528/
https://www.ncbi.nlm.nih.gov/pubmed/35739318
http://dx.doi.org/10.1038/s41556-022-00940-w

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