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Actin remodelling controls proteasome homeostasis upon stress

When cells are stressed, bulk translation is often downregulated to reduce energy demands while stress-response proteins are simultaneously upregulated. To promote proteasome assembly and activity and maintain cell viability upon TORC1 inhibition, 19S regulatory-particle assembly chaperones (RPACs)...

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Detalles Bibliográficos
Autores principales: Williams, Thomas David, Cacioppo, Roberta, Agrotis, Alexander, Black, Ailsa, Zhou, Houjiang, Rousseau, Adrien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276530/
https://www.ncbi.nlm.nih.gov/pubmed/35739319
http://dx.doi.org/10.1038/s41556-022-00938-4