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Actin remodelling controls proteasome homeostasis upon stress
When cells are stressed, bulk translation is often downregulated to reduce energy demands while stress-response proteins are simultaneously upregulated. To promote proteasome assembly and activity and maintain cell viability upon TORC1 inhibition, 19S regulatory-particle assembly chaperones (RPACs)...
Autores principales: | Williams, Thomas David, Cacioppo, Roberta, Agrotis, Alexander, Black, Ailsa, Zhou, Houjiang, Rousseau, Adrien |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276530/ https://www.ncbi.nlm.nih.gov/pubmed/35739319 http://dx.doi.org/10.1038/s41556-022-00938-4 |
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