Ductal keratin 15(+) luminal progenitors in normal breast exhibit a basal-like breast cancer transcriptomic signature

Normal breast luminal epithelial progenitors have been implicated as cell of origin in basal-like breast cancer, but their anatomical localization remains understudied. Here, we combine collection under the microscope of organoids from reduction mammoplasties and single-cell mRNA sequencing (scRNA-s...

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Detalles Bibliográficos
Autores principales: Kohler, Katharina Theresa, Goldhammer, Nadine, Demharter, Samuel, Pfisterer, Ulrich, Khodosevich, Konstantin, Rønnov-Jessen, Lone, Petersen, Ole William, Villadsen, René, Kim, Jiyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276673/
https://www.ncbi.nlm.nih.gov/pubmed/35821504
http://dx.doi.org/10.1038/s41523-022-00444-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276673/
https://www.ncbi.nlm.nih.gov/pubmed/35821504
http://dx.doi.org/10.1038/s41523-022-00444-8

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