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PGC-1α induced mitochondrial biogenesis in stromal cells underpins mitochondrial transfer to melanoma
INTRODUCTION: Progress in the knowledge of metabolic interactions between cancer and its microenvironment is ongoing and may lead to novel therapeutic approaches. Until recently, melanoma was considered a glycolytic tumour due to mutations in mitochondrial-DNA, however, these malignant cells can reg...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276678/ https://www.ncbi.nlm.nih.gov/pubmed/35347324 http://dx.doi.org/10.1038/s41416-022-01783-w |