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Integrating digital pathology and mathematical modelling to predict spatial biomarker dynamics in cancer immunotherapy

In oncology clinical trials, on-treatment biopsy samples are taken to confirm the mode of action of new molecules, among other reasons. Yet, the time point of sample collection is typically scheduled according to 'Expert Best Guess'. We have developed an approach integrating digital pathol...

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Detalles Bibliográficos
Autores principales: Hutchinson, L. G., Grimm, O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276679/
https://www.ncbi.nlm.nih.gov/pubmed/35821064
http://dx.doi.org/10.1038/s41746-022-00636-3