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Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration

The kidney has tremendous capacity to repair after acute injury, however, pathways guiding adaptive and fibrotic repair are poorly understood. We developed a model of adaptive and fibrotic kidney regeneration by titrating ischemic injury dose. We performed detailed biochemical and histological analy...

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Detalles Bibliográficos
Autores principales: Balzer, Michael S., Doke, Tomohito, Yang, Ya-Wen, Aldridge, Daniel L., Hu, Hailong, Mai, Hung, Mukhi, Dhanunjay, Ma, Ziyuan, Shrestha, Rojesh, Palmer, Matthew B., Hunter, Christopher A., Susztak, Katalin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276703/
https://www.ncbi.nlm.nih.gov/pubmed/35821371
http://dx.doi.org/10.1038/s41467-022-31772-9