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Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration
The kidney has tremendous capacity to repair after acute injury, however, pathways guiding adaptive and fibrotic repair are poorly understood. We developed a model of adaptive and fibrotic kidney regeneration by titrating ischemic injury dose. We performed detailed biochemical and histological analy...
Autores principales: | Balzer, Michael S., Doke, Tomohito, Yang, Ya-Wen, Aldridge, Daniel L., Hu, Hailong, Mai, Hung, Mukhi, Dhanunjay, Ma, Ziyuan, Shrestha, Rojesh, Palmer, Matthew B., Hunter, Christopher A., Susztak, Katalin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276703/ https://www.ncbi.nlm.nih.gov/pubmed/35821371 http://dx.doi.org/10.1038/s41467-022-31772-9 |
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