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Multi-omics profiling of collagen-induced arthritis mouse model reveals early metabolic dysregulation via SIRT1 axis

Rheumatoid arthritis (RA) is characterized by joint infiltration of immune cells and synovial inflammation which leads to progressive disability. Current treatments improve the disease outcome, but the unmet medical need is still high. New discoveries over the last decade have revealed the major imp...

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Detalles Bibliográficos
Autores principales: Li, Lingzi, Freitag, Janina, Asbrand, Christian, Munteanu, Bogdan, Wang, Bei-Tzu, Zezina, Ekaterina, Didier, Michel, Thill, Gilbert, Rocher, Corinne, Herrmann, Matthias, Biesemann, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276706/
https://www.ncbi.nlm.nih.gov/pubmed/35821263
http://dx.doi.org/10.1038/s41598-022-16005-9