Altered m6A RNA methylation contributes to hippocampal memory deficits in Huntington’s disease mice

N6-methyladenosine (m6A) regulates many aspects of RNA metabolism and is involved in learning and memory processes. Yet, the impact of a dysregulation of post-transcriptional m6A editing on synaptic impairments in neurodegenerative disorders remains unknown. Here we investigated the m6A methylation...

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Detalles Bibliográficos
Autores principales: Pupak, Anika, Singh, Ankita, Sancho-Balsells, Anna, Alcalá-Vida, Rafael, Espina, Marc, Giralt, Albert, Martí, Eulàlia, Ørom, Ulf Andersson Vang, Ginés, Silvia, Brito, Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276730/
https://www.ncbi.nlm.nih.gov/pubmed/35819730
http://dx.doi.org/10.1007/s00018-022-04444-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9276730/
https://www.ncbi.nlm.nih.gov/pubmed/35819730
http://dx.doi.org/10.1007/s00018-022-04444-6

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